Overview of Chosen Chemical Compounds and Intermediates

Overview of Chosen Chemical Compounds and Intermediates

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1. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This is often an impurity associated with bortezomib, a proteasome inhibitor used in the remedy of several myeloma. Its synthesis or review is critical for making certain the purity and safety of your drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-7): A precursor within the synthesis of abiraterone acetate, a drug Employed in the remedy of prostate cancer by inhibiting androgen creation.
Imatinib Intermediate (CAS NO. 152460-ten-1): A vital compound during the synthesis of imatinib, a drug that targets certain sorts of most cancers, which include Persistent myelogenous leukemia (CML).
Docetaxel Intermediate: A compound Utilized in the synthesis of docetaxel, a chemotherapy medication that treats numerous cancers such as breast, lung, and prostate cancer.
two. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, eight): These are intermediates during the synthesis of gemcitabine, an anti-most cancers drug. Their review is crucial for optimizing the output course of action and making certain large purity.
Lapatinib Intermediate (CAS NO. 231278-eighty four-5): Lapatinib is utilized to deal with breast most cancers, and these intermediates are involved in its production.
Fulvestrant Intermediates: Fulvestrant is definitely an estrogen receptor antagonist used in the remedy of breast most cancers. A variety of intermediates help in the synthesis of this drug.
Paclitaxel Side Chain Acid (CAS NO. 949023-sixteen-9): This intermediate is Employed in the synthesis of paclitaxel, a chemotherapy drug helpful in treating cancers for example ovarian, breast, and lung most cancers.
three. Other Noteworthy Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-3): A chemotherapy drug Employed in the treatment of colorectal 17-(3-pyridinyl)- cancer and tiny cell lung cancer.
three-Amino-1-hydroxyadamantane (CAS 702-eighty two-9): This compound is involved in the synthesis of adamantane derivatives, which have a variety of applications, together with antiviral Qualities.
Vildagliptin Intermediates: Employed in the production of vildagliptin, an oral drug for form 2 diabetes that inhibits the enzyme DPP-4 to manage blood sugar stages.
4. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-forty eight-one): This compound is involved with the synthesis of varied gluconic acid derivatives, that are Employed in food stuff, 5-dibenzoate(T6) pharmaceutical, and industrial apps.
Canagliflozin Intermediate two: A precursor in the synthesis of canagliflozin, a medication made use of to handle kind 2 diabetes by inhibiting sodium-glucose co-transporter two (SGLT2).